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KMID : 0984920110130010020
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Journal of Skin Barrier Research
2011 Volume.13 No. 1 p.20 ~ p.24
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Recent Advances in "Skin Barrier" Research
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Bak Ha-Na
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Abstract
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The stratum corneum, at the interface with the environment and highly specialized to deal with a multitude of environmental challenges, has recieved a great deal of attention. Researches on the stratum corneum biology and chemistry has greatly progressed over the last decade. Recent researches about stratum corneum maturity in relation to desquamation and barrier function, filaggrin biology, natural moisturising factors, stratum corneum proteases, and emerging researches about antimicrobial barrier are discussed. This short review gives a overview of the entire skin as an integrated system having multiple barrier functions harmonized to provide the nessesary defensive mechanisms. But, despite our increasing knowlege of the stratum corneum biology, we are still far from understanding the exact control mechanisms in skin barrier.
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KEYWORD
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Skin barrier, Stratum corneum
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